Composition: Enclex 40 : Each prefilled syringe contains Enoxaparin Sodium IP -40mg Water for injection IP -0.4ml Enclex 60 : Each prefilled syringe contains Enoxaparin sodium Sodium IP -60mg Water for injection IP - 0.6ml Dosage form: Pre-filled syringe Pharmacology : Enoxaparin is a low-molecular weight heparin ,which has anti- thrombotic properties .In humans, enoxaparin given as a subcutaneous dose of 1.5 mg/kg is characterized by a higher ratio of anti- Factor X a to anti-Factor II a activity. Distribution: The volume of distribution of anti- Factor Xa activity is about 4.3 litres Metabolism: Enoxaparin Sodium is primarily metabolized in the liver by desulfation and /or depolymerization to lower molecular weight species with much reduced biological potency.Renal clearance of active fragments represents about 10% of the administered dose and total renal excretion of active and non-active fragments 40% ...
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